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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDX6
All Species:
52.73
Human Site:
S166
Identified Species:
77.33
UniProt:
P30041
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30041
NP_004896.1
224
25035
S166
E
I
L
R
V
V
I
S
L
Q
L
T
A
E
K
Chimpanzee
Pan troglodytes
XP_001148286
209
23201
S146
P
D
K
K
L
K
L
S
I
L
Y
P
A
T
T
Rhesus Macaque
Macaca mulatta
XP_001101473
224
25004
S166
E
I
L
R
V
V
I
S
L
Q
L
T
A
E
K
Dog
Lupus familis
XP_537190
245
27431
S187
E
I
L
R
V
I
T
S
L
Q
L
T
A
E
K
Cat
Felis silvestris
Mouse
Mus musculus
O08709
224
24852
S166
E
I
L
R
V
V
D
S
L
Q
L
T
G
T
K
Rat
Rattus norvegicus
O35244
224
24800
S166
E
I
L
R
V
V
D
S
L
Q
L
T
A
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515331
223
24797
S165
E
I
L
R
V
I
D
S
L
Q
L
T
A
C
K
Chicken
Gallus gallus
Q5ZJF4
224
24958
S165
E
I
L
R
V
V
D
S
L
Q
L
T
A
Y
K
Frog
Xenopus laevis
NP_001082669
224
25051
S165
E
I
L
R
V
V
D
S
L
Q
L
T
A
V
H
Zebra Danio
Brachydanio rerio
NP_957099
222
24990
S165
E
I
L
R
V
V
D
S
L
Q
L
T
A
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523463
222
24827
S164
E
I
L
R
V
I
D
S
L
Q
L
T
Q
T
K
Honey Bee
Apis mellifera
XP_395319
220
24904
S162
E
I
L
R
V
I
E
S
L
Q
L
T
E
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784500
189
21008
S132
E
I
L
R
V
I
D
S
L
Q
L
T
A
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
A2SZW8
229
24887
S170
E
V
L
R
A
V
D
S
L
L
T
A
A
K
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04005
216
24063
S156
E
V
L
R
A
L
D
S
L
L
M
A
S
K
H
Baker's Yeast
Sacchar. cerevisiae
P34227
261
29477
T191
K
K
I
R
L
I
F
T
Y
P
S
T
V
G
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.3
98.6
84.9
N.A.
89.7
91.5
N.A.
85.2
86.1
80.3
73.6
N.A.
60.2
59.3
N.A.
58
Protein Similarity:
100
87.5
99.5
89.3
N.A.
93.7
95
N.A.
91.5
93.7
87.5
86.1
N.A.
70
72.7
N.A.
63.8
P-Site Identity:
100
13.3
100
86.6
N.A.
80
80
N.A.
80
86.6
80
86.6
N.A.
73.3
66.6
N.A.
80
P-Site Similarity:
100
40
100
93.3
N.A.
80
80
N.A.
86.6
86.6
80
86.6
N.A.
80
80
N.A.
86.6
Percent
Protein Identity:
N.A.
51.5
N.A.
50.4
42.5
N.A.
Protein Similarity:
N.A.
67.6
N.A.
66.5
56.3
N.A.
P-Site Identity:
N.A.
46.6
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
60
N.A.
66.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
13
69
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
0
0
0
0
63
0
0
0
0
0
0
0
0
% D
% Glu:
88
0
0
0
0
0
7
0
0
0
0
0
7
19
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% H
% Ile:
0
75
7
0
0
38
13
0
7
0
0
0
0
0
0
% I
% Lys:
7
7
7
7
0
7
0
0
0
0
0
0
0
19
57
% K
% Leu:
0
0
88
0
13
7
7
0
88
19
75
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
7
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
75
0
0
7
0
0
% Q
% Arg:
0
0
0
94
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
0
0
94
0
0
7
0
7
7
0
% S
% Thr:
0
0
0
0
0
0
7
7
0
0
7
82
0
32
7
% T
% Val:
0
13
0
0
75
50
0
0
0
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _